Explore the science

Discover the research, ingredients and thinking behind Creatonics.

How we designed Creatonics

1

Identify the changes

We started by looking at the physiological changes that most influence women's healthspan and quality of life in midlife.

The changes we identified

  • Sarcopenia (muscle loss)
  • Loss of bone mineral density
  • Cognitive sharpness (the emergence of brain fog)
  • Sleep disruption
2

Map the systems

Having identified those changes, we mapped out the systems most relevant to them.

The systems we focused on

Strength

Strength

Bone health

Bone health

Energy

Energy

Clarity

Clarity

Recovery

Recovery

Hormonal balance

Hormonal balance

3

Build the formula

We then researched & selected the most robustly-evidenced nutrients, minerals, and botanicals to support those systems through a simple day-and-night routine.

Explore the ingredients

Why creatine?

Strength & performance

Creatine helps your muscles produce energy, making it one of the most well-researched supplements for supporting strength, exercise performance and resistance training.

Particularly relevant for women

What makes creatine particularly important for women is that women have been reported to have up to 80% lower natural creatine stores than men.

Creatine is also found mainly in meat and fish, which women often eat in smaller amounts.

Beyond just muscle

Emerging research is also exploring the wider benefits of creatine for women over 35, including its potential role in bone health, brain function and resilience to sleep deprivation.

Why 10g rather than 5g?

Creatonics is designed around the Day and Night system: 10g daily, split into two 5g servings.

This reflects emerging research using higher intakes for brain energetics.

Ingredient deep dive

Day

Night

Ultrapure Creatine Monohydrate (Micronised)5g

Dose | 5g

At the centre of Creatonics is creatine: one of the most researched ingredients in nutrition. We include it to support strength, physical performance and long-term resilience through midlife

The Science: Creatine is essential for ATP (cellular energy) regeneration. While traditionally used for muscle strength, research highlights its critical role in supporting the brain’s "energy buffer," helping to mitigate the mental fatigue often associated with hormonal shifts.

Why Micronised? We use a micronised form with smaller particles for superior solubility and easier digestion, avoiding the "grittiness" of standard powders.

Zensera™ Lemon Balm Extract300mg

Dose | 300mg

The Science:
Zensera® is a standardised extract of Melissa officinalis developed to support cognition under stress. It has been studied for its effects on mental performance, with particular relevance to focus, calmness and cognitive clarity.

The Benefits: It is clinically shown to support cognitive performance and mental clarity under situations of stress by modulating GABA activity. For the midlife woman, this means support for "focused energy" without the jitters.

Vitamin D325µg

Dose | 25µg (1000IU)

The Science: Vitamin D3 supports normal calcium absorption, normal muscle function and the maintenance of normal bones. Because vitamin D helps increase calcium availability, it works especially well alongside vitamin K2, which helps activate proteins involved in directing calcium appropriately within the body.

The Benefits: For women in midlife, vitamin D3 helps support the foundations of strength, movement and long-term skeletal health. Paired with vitamin K2, it forms a more complete approach to calcium metabolism, bone health and daily physical resilience.

Vitamin K2100µg

Dose | 100µg

The Science:
Vitamin K2 supports the maintenance of normal bones and contributes to normal blood clotting. It is also involved in activating vitamin K-dependent proteins, including those linked to calcium handling, helping the body direct calcium towards the skeleton where it is needed most.

The Benefits: For women in midlife, vitamin K2 is a highly relevant partner to vitamin D3. Together, they help create a more intelligent approach to bone health, supporting the structure, stability and long-term physical resilience that become increasingly important with age.

Activated B-Vitamins (B2, B6, B7, B9, B12)

Doses

  • B2 (Riboflavin) | 2mg
  • B6 (Pyridoxine) | 2mg
  • B7 (Biotin) | 30µg
  • B9 (Folate) | 400 µg
  • B12 (Cobalamin) | 2.5µg

The Science: B vitamins play essential roles in energy metabolism, nervous system function and psychological function. We use methylated, bioactive forms to provide a more effective and considered nutritional foundation.

The Benefits: This blend helps support steadier energy, mental clarity and daily resilience - making it easier to feel capable, sharp and well-supported through the demands of midlife.

Ultrapure Creatine Monohydrate (Micronised)5g

Dose | 5g

At the centre of Creatonics Night is creatine: one of the most researched ingredients in nutrition. We include a second 5g serving to support daily creatine saturation, helping replenish the body’s energy systems as part of your evening routine.

The Science: Creatine is essential for ATP regeneration, the rapid energy process used by both muscles and the brain. While best known for physical performance, emerging research suggests creatine may also help support cognitive performance when the brain is under energetic stress, such as after disrupted or insufficient sleep.

Why Micronised? We use a micronised form with smaller particles for improved solubility and easier digestion, helping avoid the “grittiness” often associated with standard creatine powders.

SheVari4™ Shatavari Extract100mg

Dose | 100mg

The Science:
Shatavari is an adaptogenic herb with a long history of use in Ayurvedic practice, and SheVari4™ is a standardised extract developed specifically for modern women’s health applications.

The Benefits: SheVari4™ is a standardized extract specifically shown to support hormonal balance and mitigate common menopausal symptoms.

Magnesium Bisglycinate1.5g (300mg Elemental Magnesium)

Dose | 1.5g (300mg Elemental Magnesium)

The Science:
Magnesium is involved in hundreds of enzymatic processes, including muscle function, nervous system regulation and energy metabolism. We use the bisglycinate form because it is well tolerated, highly bioavailable and especially well suited to an evening formula.

The Benefits: Magnesium supports muscle relaxation and the winding-down process that helps prepare the body for rest. It brings a calmer, steadier feel to the night formula while supporting recovery and restoration.

Zinc10mg

Dose | 10mg

The Science: Zinc is an essential mineral involved in immune function, cognitive function, normal DNA synthesis and cellular repair. It also contributes to the maintenance of normal bones, skin, hair and nails.

The Benefits: Included in the evening formula, zinc supports the body’s overnight repair processes while reinforcing the wider foundations of daily wellness, resilience and healthy ageing.

Explore the research behind the formula

Behind every ingredient sits a body of research. We're building a searchable library so you can explore the evidence by ingredient, health area, evidence type and claim status.

View research database Close research database
IngredientHealth areaEvidence typeApproved claimEmerging research

Built around the biology of midlife. Designed for daily use.